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  PORTFOLIO COMPANIES:

|  Software & Applications

|  IT Services

|  Storage/Communications

|  Life Sciences
    Life Sciences

ARCA biopharma

Business: Drug discovery based on pharmacogenomics of heart disease.
Co-investors: Atlas Ventures; Pequot Ventures
   
   
Array Biopharma

Business: Array is a discovery research organization that sells chemicals and services to the pharmaceutical industry.
Update: IPO November 2000 (NASDAQ:ARRY)
Co-investors: Falcon Technology Ventures; Frazier & Co.; ARCH Ventures; Advent International; Mitsui & Co. USA
   
   

Barofold

Business: Barofold will commercialize patented technology that will dramatically improve the cost of purity and manufacturing protein molecules.
Co-investors: HBM Partners

   
   
Dharmacon

Business: Leading supplier worldwide of synthetic RNA
Update: Sold to Fisher Scientific March 2004 (NYSE:FSH)
Co-investors: Telegraph Hill Partners
   
   

Entelos, Inc.

Business: Entelos software and services offer decision-support and disease knowledge management for biopharmaceutical researchers.
Co-investors: Abingworth Management; Charles River Partners; St. Paul Venture Partners

Update: IPO on London AIM 4/06

   
   
Genomica

Business: Genomica's database software, Discovery Manager, allows researchers to organize and analyze genetic sequences for drug discovery.
Update: IPO (NASDAQ:GNOM); Sold to Exelixis, November, 2001
Co-investors: Falcon Technology Partners; ARCH Venture Partners; INVESCO Trust Company; The Kaufmann Fund
   
   
Millennium Pharmacy Systems, Inc.

Business: Millennium Pharmacy Systems offers technology-enabled institutional pharmacy services.
Co-investors: CHL Medical Partners
   
   
Hiberna Corporation

Business: Drug development based on novel model organisms that exhibit profound biology.
Co-investors: Peierls Foundation
   
   
MiRagen Therapeutics

Business: MicroRNA applications in cardiovascular disease.
Co-investors: Atlas Venture
   



 
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